Hebron, also called Kiryat Arba, is a city designated for the Kohanim as well as a city of refuge and is located in the tribal territory of Yehuda. 

Currently identified with Tel Rumeida (Y. Aharoni).

Hebron was both a dwelling and burial place for the forefathers (See Genesis 13, 18; Genesis 23, 2; Genesis 35, 27; and elsewhere in Genesis).
Abraham bought the Cave of Makhpela (the "double cave", "Me'arat ha-Makhpela" in Hebrew), located in Hebron, from Ephron the Hittite as a burial plot for Sarah(Genesis 23, 2-20).
Hebron was described as being inhabited by giants (Numbers 13, 22; Joshua 14, 15).
Yehoshua captured Hebron and gave the city to Calev ben Yefuneh (Joshua 10, 36-37; Joshua 11, 21; Joshua 14, 13-14; Joshua 15, 13; Judges 1, 20).
David began his reign by ruling in Hebron (II Samuel 2, 1-4; II Samuel 3, 19; I Chronicles 11, 1-3).
Avshalom instigated his rebellion in Hebron  (II Samuel 15, 7-10).
King Rehavam of Yehuda fortified Hebron (II Chronicles 11, 10).
Jews inhabited Hebron during the period of the Return to Zion (Nehemiah 11, 25).

For further reference, see:

אבי עופר, "הר יהודה המקראי", נדפס ב'מנוודות למלוכה: היבטים ארכיאולוגיים והיסטוריים על ראשית ישראל', עמ' 190-194.